Selective G-quadruplex binding by oligoarginine-Ru(dppz) metallopeptides
نویسندگان
چکیده
منابع مشابه
Discovery of new G-quadruplex binding chemotypes.
We report here on the discovery and preliminary evaluation of a novel non-macrocyclic low molecular weight quadruplex-stabilizing chemotype. The lead compounds, based on a furan core, show high G-quadruplex stabilisation and selectivity as well as potent in vitro anti-proliferative activity.
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ژورنال
عنوان ژورنال: Chemical Communications
سال: 2018
ISSN: 1359-7345,1364-548X
DOI: 10.1039/c7cc08286j